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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d1225fe4f01b2bfcaf722448061a69a983a3a7adfc2b5c00d0da8d22280e5d' 
  AND token = 'gMqvjJcnJKU0qtDKpFEl+J54lcmRTcNKMkHJ+e1LheI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}