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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20603d4f49f478d21af3a28b84aedc117320b6f0c41ba8f566857d6b357e6375' 
  AND token = '+ICGauhm8NDlOxf4G8Ga9DdHcsJyfEMQ3ZHXVeeH18Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}