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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fac668f0008da94664d8cd940e37e8c4e163d9f0fd0610ebda54eebd0988070' 
  AND token = 'QhEdPF7bDSWW0lTbA6RuEI6GkZyNz0FPq9d2T8swHBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}