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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd964e8c4a749fef9747b512c1455a9c73ca6ee07e8e5edd957eec87edbe9a6e1' 
  AND token = 'zULf4XfjhxFBwFLKzpbrNt17GsHnc0xuyfC4XNYYUWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}