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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ff9cde075588b81c5a90500974f9912f8e536952215b5e29519f38f56d3134' 
  AND token = 'ukIzN4dZHclEpqLZ2Fs/h+qm0D81AI28tZMLMQI/2iE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}