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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a039bd254bea2d15100f77f4d6cb256d5467431b9d095caf83c0df209fe1154b' 
  AND token = 'wQGTzGH/SNtkbQ+b6UOGW/gkaBFoK74nUqEk7P6bB7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}