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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da4307be257a73dd17df8d2f1efc8dcefadea1d624e9fb848fcc2951cabb62b4' 
  AND token = 'BVBQpQFeq15Usyl/z/zj0hUFR7VvA0OktAxo5L7mSL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}