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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53272bd37cdd3f44b444f22b7b94545ed5f9b786de1f3df221c7ea8692977e2d' 
  AND token = 'nID1D7Cy4kC2b9hmRWXmi11nVyfa0iHHbgnCN37qC+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}