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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9b74d2d3c0a8f7e528273a50565af5da69ff26902c01cb8a604d0f48c55483' 
  AND token = 'p4jZUnJ3KuM3u3W3mxkPgfGk6IRaKxenV1wO3YXyRMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}