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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c4f2a156d58bf1b6abbe4f0ed3cfdc32337262fb182918bdb84d865f6d5b401' 
  AND token = 'V7OfMYsJDNVLH/f6Wl6mdc/i+JHWtYeTrBrRvaL7bfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}