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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4e1a00fbe5eca86e8de59c6d9047110fafdf1c4598d71020b591081610d0f35' 
  AND token = 'tkN2PU8pq+e6DnnV/Mjvm6wqdLSWDKii9e/l8ECTkH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}