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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '464ae8786f84d4e54d42480cc9a275e066d379ae54a92220a8847536173872a1' 
  AND token = 'ZdxzGjdy/Q+HF2Z6IQp6E29U4aGhELfGwSvsvGyTekQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}