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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e5cdb772a6fee702e9a55e0bcb36541e698e09938dba749ee4e2cb61cc3b679' 
  AND token = 'P95IUgEna60dLT/c/KsZq3xSn66v1wAi0S1ufa0dciU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}