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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '425d6d5cb27e3753d98c5398b40e9223475164b6cbb14da4efe21af54059fe4c' 
  AND token = 'hSWardh8aiESYwbfBHBdu2sX/dXCK2U7KqtblEqAd6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}