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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c21eb782d6438f2c03ff0ce18daa784079e867a7286e58d66a9511dfaa8d05' 
  AND token = 'Qhjr1+iu7cUYO7ruIaan7ilWNWl+AZZjYsCqPw8KBTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}